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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443d3ebeb4d6ba58c5407f72fec9014641064b53f42a0c139e4f537186e092f1' 
  AND token = 'IDqbQ7fvb2yBFXOELKI1ifxJujpq0DxDrSLjKD6xzqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}