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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efc8fbb640b29c92b4ffd55f00e4dd27b347b74356beac660277fc08d016ee0' 
  AND token = 'TdpETn0+evF38Nrz6ElI9DMoH426OWvxAIcckG5ihFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}