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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164af321c17790c0355b238a49f701d97f23f79992eb9d20a3c2a2d558f5b412' 
  AND token = 'b7h018pgM19b1NprRdRy7TOQXkwJw77B/yTR4fBhtK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}