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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cae13ca5db5b80c39124651bb272470002f7fb82b32f505b0313e125919ca8f' 
  AND token = 'E3aGBJAZ3DlUXuEUOn89YWFjhF5A9XEGPcMlU1s2C6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}