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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d034717c3e27dbea36d01c5057126c195e9717410fd86665c38254d7e25e5d2' 
  AND token = 'dlq7aKEcdnIjDugIGBtc4vD4hZVUZNa3G7Z9pOQoCN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}