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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e856e9e3d3d25ce06f55a48ed0196218dc3799676a7ebc1d57c62d095fc498b' 
  AND token = 'zIwfI379/pU198X3Uwz1kFWzKgkhtHlC/5gRiXaQNnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}