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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19573a9159abf960e960dc8b6c9944b3ae96ff44ddd20136220c09da84f24ce2' 
  AND token = 'Haq0Yr94460fIUya+iG/iDfwVUXimYO8cDo624kzSEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}