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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5083bad1df1de17755955500f2cf8cc9dd1947bd12854e2f28acb711c96f1931' 
  AND token = '0qwXJ9lbsSJbMzqMz4iWS489tSMv2LtzWF6CqcVcpO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}