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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe366a10beb2872ce00fafbebaebb5473adbb5af2a7b73ca6c3a0821194c6a47' 
  AND token = 'NwRfKci7m0ghnUFxfVC5VOn2uCd8SxT+rRk9rjqF2l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}