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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c442b8a58f77ca23058b9e30c424043ac581371bc2de40ca51ddef3087b8762d' 
  AND token = '+hUNg7nRYY+E3U9Rv0kZ9R/iMHlhdhE/mbWXTqjQcfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}