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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef16928c9901371fcf32b90b165a3d5008cace8c0e5f0fc0dc728f645cec56c2' 
  AND token = 'MMjPL6fCYA8PuQPwDScGZ+DR+CGdIeYFFND3DgjT3Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}