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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b2fba4a4f0909a690258627116c8b274b437d992c39f9fa924fe6335b2b052' 
  AND token = '2eZ7DNKLscdTuukyp+0UvcbkqQ0XLpDL0FKDnCLBgC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}