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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62151097f3b525159a61399b7586a304a3f95b2cef3e5df3c5e068da3be55a0a' 
  AND token = 'y+Q2rD7kt8j9qGf+p7ECB52KA5PwC4WlYnTjE4NtBXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}