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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06420255a6db4d3a3fe1e14c7030a33b36c4e3396f03a1359ee53e1f4cba2bb6' 
  AND token = 'CqmuL8Rsv1gxOTohz2vnx0ktNgMmrUjHP9XCvcd5e1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}