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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7668a7709e9052b4c200c18549ed24528ae43ebb7d6bf5e6a8c8d3caba2a4556' 
  AND token = 'zK4za/tIe9riRB8bJ227BGY2si4ebaFQU9hDblfpjDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}