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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418ec7443d7a171d63b141f63a425f030d4e3cb0bcdb6d289d6445e757757e4f' 
  AND token = '2wHcM73o9cWDD0+I7Jd3mOqcQjWuV2/eExwVmKu9n3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}