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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0a8c01bfa1e0eb36f260ff4725bc27ea4c81f87eeac49fb7fb53d39227d173d' 
  AND token = 'JbzRuMcyGKm7zsiFZt9Sb6rPgQ9zC6kqkkLI0QT+VN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}