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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34b30d0edf99de6458e060c5fc0729e2c7cdb0c1b4961ac6bc1315fabe3677f6' 
  AND token = 'USkuoKNyb2BIygoy7vUtQ4KzCV0hk0PZlKCrZsHxuOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}