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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd242c50267249589c6155c097a5dee1e2a3a56e5f03c1a9ef5f74bcc5c9b60' 
  AND token = 'Khm2ztSvM0fbWVGp5AmfXrokLEZa5Iw0Y9EhKgyFzWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}