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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9d518c6a05ac222100b75e1d8217108b23264b2519108dfe0967f681538cdb5' 
  AND token = 'UphZKZL33O4HIHswdiLEJ+2R7gchy0qNEuEnSzDHNOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}