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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819a76ef573aebb597eae77bad82b89a5fe031e7bb3fe6452efe02073170ff3e' 
  AND token = 'v/Wl1TZcqNXWogT1ZvQJqXHNy1MzXu6YgP6yUFwZg30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}