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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '952a2c28e736b902e1572833fd4e51287536bdf0041e40e906fd10684aa8ebe2' 
  AND token = 'EoIpwzVkxMcoAR18Pm+WkWCk++xDR4RUJOuBkYDvS6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}