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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5dd0100bd9bfcf4041fb38b2969cd2bbb7188b794aea9ce3117a6b67db30288' 
  AND token = 'yqaDdFLCI/QlV+eIeIC7XSPfFBA5g4SH9V3iwAA2ejY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}