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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b806e4ee188feae16db768cbb9e44683035380f93a1421e7f8ee35f75a8191' 
  AND token = 'As2ht+1QrgpTRn7HJW7USaD0i4eUcdVXBh5Ez6zpm1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}