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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c12d2390282cca8f21d42c596ed6123bf026443b6b482192d6c7d017fdd1050' 
  AND token = 'KHrkVIq59hVm92Fkr2SoPR7slU5VeOB9k2WXewVtXuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}