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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b5d054887c2f89ad7772f2d7e3afd261de5ac6f2ce3baec1ca6245b9883061' 
  AND token = '+HGdMLvF6vSn7WHAifMWQ5K1THQe2/hKv3ty762Psc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}