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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810d52500287e919bf81f13909536421f145d754c6f369e50fb3cf216c1dfa6c' 
  AND token = '0c+fu6qoyTatoejWPVpmEpWd/2BR1fo0KzOwTsfVNhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}