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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e581f130ce9f38f401bf10c65f27c8d1a8b4bd1e624aa163f8a188cfceaec35e' 
  AND token = 'By68WSwYTll+mpwnRhF2XPuk8M3c2CbWh/cYhQorOHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}