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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21f326207a0ae423abad5c24bccf8485d33e1404479b7d1f1c102a1c9a57db9' 
  AND token = 'gBpIZHpvctA/Ky6/QlpwlkW3EiVStoK/s0mUxt/8MfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}