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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7d146c6fa4d7bd9b7a6d35049204c5be9dc29ff81d5649b6a85a111a5c91f81' 
  AND token = 'b+Sw3kG0GFOTKF59i4MrwlMCH9e4uL/WeQK0MqSkgZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}