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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fc495e8023a2cd846f3b199ad5dc686b0b6fd2e86102088a80746e089baed03' 
  AND token = 'LjwmKFDdWf4C0HFv5bKQdvwtRErEDKl1/O9mSrQ4nEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}