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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c293ea5eb4ee69b0e9a57f2cd0f4894543d0691a239d31f03f650c2b31568a91' 
  AND token = 'pYEeRVQsYc+oecw+2wC9q7QAYQAIz7NEGw6ku6K/ih8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}