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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77ff1d7fc3ad1350b4238899056b001024096aedaf4094b9f4778a5e0673e8ca' 
  AND token = 'TYDuFOsyXARkL2L1FwOy3h00NdXBB+/TAt5saNh6T7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}