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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f64f013821856c0710dc096893409e7823a1a069c746ca9d0a652b371ca0068f' 
  AND token = 'DFknj0piucpXu1Pz7R/Id+qkfhbw+Cbc9wIldv1c0ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}