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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a0a87c1fb84e37ddc53aa10051f0c4535b45edbcccd631834529e904a3ad61' 
  AND token = 'P9agpO99xm6tIf+VN19KdhzyH/Tv0m0yB5r+vtbNOVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}