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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c11cf1855430fd7d738e90f034301cc58df4bb01862d9a7301c93a0fe52a6f' 
  AND token = 'NKF+OmHyr0eA6hHgiUoU6RdJB4u5W8UW98uE62qOOx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}