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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b981f018064c6c33edde988dee04118851db9f416b4c34f155304ea237ae586' 
  AND token = 'vy+bBjcn4o8A6pNcW9xEF0REpSO1gir4WAXDTX/1KdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}