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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e91408019c23249d7aca5380720f623ed03d5304810c7b719810327f8f787f66' 
  AND token = '+HCN3eJDUh6ZK8vFgITy2/hr8GSvIGOMSZxKOGKHRy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}