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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c82c8f85f16f5a771604aa872a65b79019f7ec5b85e1fa39f21824865b416a' 
  AND token = 'o7CG1KdJJBXN1Q0IJhPhoWrbyJ91m4ILVlyGAq5gn38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}