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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de09961daf5cba1aa926db3867cb37e470b0cfcb19d7e112496949eb2d0ece5c' 
  AND token = 'PgBsE+Y5gKU4Ac6ZwVjYxLQMN9GTljphAlkKAt0ofss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}