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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be53f6e90aa40a499c4cf6968b6f0f424da43330f0f7114e8559af497e32252' 
  AND token = 'a//aqXVaFYe5wwOErACLmALaKooM6W/icUkbFXgI9Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}