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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052c549f333e8c28be780b08dd01829ec4990a4566b2f827bf8e285578c32d20' 
  AND token = 'tEZdOsC2fl1mZMiVZGgEgZ6oZXUhrlKP119Uidc9poc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}