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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1011dc8929511bd1770b55c36cffa6ce6ab07e9a75b22a8b63f4dc7b1010679a' 
  AND token = 'offjES8vB6ZAgWF6rFer0hi00IQX7LC6NMDC3dFTSrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}