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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e67ed9f5bbf3a67adc3f81adad3e29cc18f697c888df10a2481875b52210f1' 
  AND token = '54fmJR1rSslIKcgco2jtJGUiewP44kRM0MP3zkd+z40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}