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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e8e9ae5e65130542ceaf2a2241a17895d39bf59f21c0ec21bba79c4d075661' 
  AND token = 'jWL00Dusi67AGgYT6VK93lqXpJfUH3sZJcoTMaCO3+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}