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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5215350cf8c23d660f31a464fa174075edd91056e46ccec890b482c5a4d5945f' 
  AND token = 'fOHCe4Mg67uNpsW07FpeD2cEC+reQYq4Ys0fCA4PEt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}