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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e728d781ac2ba22c8f2dfda8aa138b723f7f927c89c9bba02f0b3203b83863d' 
  AND token = 'dZGz7q7Ycm6tGlwWHYzOk1CQi3fL7eWht3isbf8SGSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}