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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '712e5b5af996d49044b72c218d1b783a1707893b6fbf8593fd2760f42cd6c009' 
  AND token = 'k29V47WnLx6Zb+KED4YNF4L+cT4xLyxZ6RqEN0TrwKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}