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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b4b2c64498f417c51df4e2fc3cd5d7af3e6dfcf6c82d8559e65ab9ee2c6a80' 
  AND token = 'QBu25nrEY1PL4zZvmUbn+RYJxk7+k3Vkp5fBCGAf0yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}