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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ec3275501c0d05a7a51556abe8c5a2be66ad57ad5f61f3d84f6b74e55a30b4' 
  AND token = 'mwVBbjhcjfz7cwRp0FHrHWo2+wnoIZEi6QPjbmi9hAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}